{"id":43494,"date":"2026-02-04T01:03:40","date_gmt":"2026-02-04T00:03:40","guid":{"rendered":"https:\/\/deutschland-nederland.eu\/projects\/orion\/"},"modified":"2026-05-08T03:09:51","modified_gmt":"2026-05-08T02:09:51","slug":"orion","status":"publish","type":"projects","link":"https:\/\/deutschland-nederland.eu\/en\/projects\/orion\/","title":{"rendered":"ORION"},"content":{"rendered":"<p style=\"text-align: justify\">Chronic total occlusions (CTOs) are severe vascular blockages that cause more than 100,000 deaths and around 6 million non-fatal complications annually worldwide. The ORION project will deliver the first CE-marking-ready robotic system specifically designed to safely and effectively cross CTOs.<br \/>\nCurrent treatments involve manually pushing stiff guidewires through calcified vessels, which often leads to perforations and failed procedures. ORION replaces this method with a compact bedside robotic system that magnetically navigates the tip of a flexible microcatheter along an AI-generated 3D path. This path is created from pre-acquired CT scans and merged in real time with live X-ray images to provide continuous visual guidance.<br \/>\nPreclinical data suggest a potential 90% reduction in perforations, a halving of procedure time to a maximum of 2.5 hours, and a decrease in radiation exposure (fluoroscopy) from several hours to a maximum of four minutes, making the procedure significantly safer for physicians and patients.<br \/>\nThe Dutch&ndash;German consortium will raise the system&rsquo;s Technology Readiness Level from TRL 5 to TRL 7 within 36 months, including validation in 20 large-scale preclinical CTO models and preparation of a complete CE-compliant technical file (ISO 13485). The project will create approximately 5.5 sustainable high-tech FTEs, strengthen three SMEs, and establish a lasting innovation ecosystem for robotic surgery in the cross-border region. Results will be disseminated through three public events, at least 30 digital outreach activities, and clear visibility for Interreg VI A.<\/p>\n","protected":false},"parent":0,"template":"","pr-category":[278],"pr-priority":[288],"pr-stat":[254],"class_list":["post-43494","projects","type-projects","status-publish","hentry","pr-category-health-care-3","pr-priority-a-more-innovative-programme-area","pr-stat-new"],"acf":[],"_links":{"self":[{"href":"https:\/\/deutschland-nederland.eu\/en\/wp-json\/wp\/v2\/projects\/43494","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/deutschland-nederland.eu\/en\/wp-json\/wp\/v2\/projects"}],"about":[{"href":"https:\/\/deutschland-nederland.eu\/en\/wp-json\/wp\/v2\/types\/projects"}],"wp:attachment":[{"href":"https:\/\/deutschland-nederland.eu\/en\/wp-json\/wp\/v2\/media?parent=43494"}],"wp:term":[{"taxonomy":"pr-category","embeddable":true,"href":"https:\/\/deutschland-nederland.eu\/en\/wp-json\/wp\/v2\/pr-category?post=43494"},{"taxonomy":"pr-priority","embeddable":true,"href":"https:\/\/deutschland-nederland.eu\/en\/wp-json\/wp\/v2\/pr-priority?post=43494"},{"taxonomy":"pr-stat","embeddable":true,"href":"https:\/\/deutschland-nederland.eu\/en\/wp-json\/wp\/v2\/pr-stat?post=43494"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}