

{"id":43233,"date":"2025-10-22T02:03:35","date_gmt":"2025-10-22T01:03:35","guid":{"rendered":"https:\/\/deutschland-nederland.eu\/projects\/precise\/"},"modified":"2026-05-08T03:09:45","modified_gmt":"2026-05-08T02:09:45","slug":"precise","status":"publish","type":"projects","link":"https:\/\/deutschland-nederland.eu\/en\/projects\/precise\/","title":{"rendered":"PRECISE"},"content":{"rendered":"<p>The surgical treatment of oncological diseases<br \/>\nposes complex challenges for modern medicine. Tumors are often difficult to<br \/>\nidentify during surgical procedures. In practice, this can lead to incomplete<br \/>\ntumor removal and postoperative complications. Existing techniques are often<br \/>\nlimited in their precision, as current marking methods are associated with<br \/>\nrisks. This is where the Interreg VI A project PRECISE comes in.<\/p>\n<p>The consortium brings together the expertise of<br \/>\ninnovative companies, certified clinical cancer centers, and experienced<br \/>\nacademic institutions. Together, they develop and evaluate new solutions for<br \/>\nmore precise tumor surgery.<\/p>\n<p>In the PRECISE project, seven partners from<br \/>\nGermany and the Netherlands collaborate closely. The consortium includes three<br \/>\ninnovative companies: K&aacute;nMedim UG, U-Needle B.V., and Chiwen B.V. It is further<br \/>\ncomplemented by the University of Groningen, the University Hospital Oldenburg,<br \/>\nthe Mathias Hospital Rheine, and the EUREGIO BioMedtech Center at FH M&uuml;nster,<br \/>\nwhich acts as the lead partner.<br \/>\nThe aim of this cross-border collaboration is<br \/>\nto sustainably improve medical care for patients with esophageal and colorectal<br \/>\ncancer. By combining medical technology, surgery, and artificial intelligence,<br \/>\nnovel solutions are being developed to make surgical procedures more precise<br \/>\nand safer.<\/p>\n<p>A key technological milestone of the project is<br \/>\nthe development of an innovative near-infrared fluorescence marker for<br \/>\nlong-term applications. This marker enables clear visualization of tumors. Even<br \/>\ndifficult-to-detect tumors become clearly visible to the surgical team,<br \/>\nsupporting complete and tissue-sparing resection.<\/p>\n<p>Building on this, ultra-fine, sharp<br \/>\nmicroinjection needles are being developed for the highly precise delivery of<br \/>\nthe fluorescence marker directly into the target tissue. Compared to<br \/>\nconventional endoscopic needles, this new technology reduces the risk of tissue<br \/>\ndamage and thereby increases patient safety.<\/p>\n<p>These innovations are complemented by the<br \/>\ndevelopment of an AI-based system for detecting the fluorescence marker. In<br \/>\nclinical practice, weak fluorescence signals are often difficult to identify.<br \/>\nThe artificial intelligence developed within the project detects such signals<br \/>\nin real time and visualizes them clearly within the surgical field. The<br \/>\ndevelopment of this system is supported by the generation of video data within<br \/>\nclinical studies conducted at the participating cancer centers.<\/p>\n<p>PRECISE is closely aligned with the needs of<br \/>\nclinical users, cancer patients, hospitals, and medical device manufacturers.<br \/>\nThe solutions developed aim to sustainably improve medical care. In combination<br \/>\nand with successful further development towards market approval, they have the<br \/>\npotential to significantly advance oncological surgery and strengthen patient<br \/>\ncare across the entire Interreg region in the long term.<\/p>\n","protected":false},"parent":0,"template":"","pr-category":[278],"pr-priority":[288],"pr-stat":[254],"class_list":["post-43233","projects","type-projects","status-publish","hentry","pr-category-health-care-3","pr-priority-a-more-innovative-programme-area","pr-stat-new"],"acf":[],"_links":{"self":[{"href":"https:\/\/deutschland-nederland.eu\/en\/wp-json\/wp\/v2\/projects\/43233","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/deutschland-nederland.eu\/en\/wp-json\/wp\/v2\/projects"}],"about":[{"href":"https:\/\/deutschland-nederland.eu\/en\/wp-json\/wp\/v2\/types\/projects"}],"wp:attachment":[{"href":"https:\/\/deutschland-nederland.eu\/en\/wp-json\/wp\/v2\/media?parent=43233"}],"wp:term":[{"taxonomy":"pr-category","embeddable":true,"href":"https:\/\/deutschland-nederland.eu\/en\/wp-json\/wp\/v2\/pr-category?post=43233"},{"taxonomy":"pr-priority","embeddable":true,"href":"https:\/\/deutschland-nederland.eu\/en\/wp-json\/wp\/v2\/pr-priority?post=43233"},{"taxonomy":"pr-stat","embeddable":true,"href":"https:\/\/deutschland-nederland.eu\/en\/wp-json\/wp\/v2\/pr-stat?post=43233"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}